SCOPe 2.08: Family c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase

Lineage for Family c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.58: Aminoacid dehydrogenase-like, N-terminal domain [53222] (1 superfamily)
   core: 3 layers: a/b/a; parallel beta-sheet of 4 strands; 2134

4. Superfamily c.58.1: Aminoacid dehydrogenase-like, N-terminal domain [53223] (6 families)

5. Family c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase [53235] (2 proteins)
   automatically mapped to Pfam PF00763

Proteins:

1. Tetrahydrofolate dehydrogenase/cyclohydrolase [53236] (3 species)
   the two-domain organization is similar to that of aminoacid dehydrogenases, but both domains are truncated

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [53239] (2 PDB entries)

   2. Species Escherichia coli [TaxId:562] [53238] (1 PDB entry)

   3. Species Human (Homo sapiens) [TaxId:9606] [53237] (7 PDB entries)

2. automated matches [346970] (1 species)
   not a true protein

   • Species Escherichia coli [TaxId:83333] [346971] (3 PDB entries)

More info for Family c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase

Timeline for Family c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase:

• Family c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase first appeared (with stable ids) in SCOP 1.55
  
• Family c.58.1.2: Tetrahydrofolate dehydrogenase/cyclohydrolase appears in SCOPe 2.07