SCOPe 2.08: Domain d5mrpa_: 5mrp A:

Lineage for d5mrpa_ (5mrp A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

4. Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (20 families)

5. Family c.68.1.13: Cytidylytransferase [68901] (7 proteins)

6. Protein 4-diphosphocytidyl-2C-methyl-D-erythritol (CDP-me) synthase (IspD, YgbP) [64140] (4 species)

7. Species Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142690] (12 PDB entries)
   Uniprot P69834 75-300

8. Domain d5mrpa_: 5mrp A: [336813]
   automated match to d1w77a1
   complexed with 6bc, cd, k; mutant

Details for d5mrpa_

PDB Entry: 5mrp, 1.9 Å

PDB Description: arabidopsis thaliana ispd glu258ala mutant in complex with azolopyrimidine (2)

PDB Compounds: (A:) 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase, chloroplastic

SCOPe Domain Sequences for d5mrpa_:

Sequence, based on SEQRES records:

>d5mrpa_ c.68.1.13 (A:) 4-diphosphocytidyl-2C-methyl-D-erythritol (CDP-me) synthase (IspD, YgbP) {Thale cress (Arabidopsis thaliana), chloroplast [TaxId: 3702]}
eksvsvillaggqgkrmkmsmpkqyipllgqpialysfftfsrmpevkeivvvcdpffrd
ifeeyeesidvdlsfaipgkerqdsvysglqeidvnselvcihdsarplvntedvekvlk
dgsavgaavlgvpakatikevnsdslvvktldrktlwemqtpqvikpellkkgfelvkse
glavtddvsiveylkhpvyvsqgsytnikvttpddlllaerils

Sequence, based on observed residues (ATOM records):

>d5mrpa_ c.68.1.13 (A:) 4-diphosphocytidyl-2C-methyl-D-erythritol (CDP-me) synthase (IspD, YgbP) {Thale cress (Arabidopsis thaliana), chloroplast [TaxId: 3702]}
eksvsvillagpkqyipllgqpialysfftfsrmpevkeivvvcdpffrdifeeyeesid
vdlsfaipgkerqdsvysglqeidvnselvcihdsarplvntedvekvlkdgsavgaavl
gvpakatikevnsdslvvktlwemqtpqvikpellkkgfelvkseglavtddvsiveylk
hpvyvsqgsytnikvttpddlllaerils

Timeline for d5mrpa_:

• d5mrpa_ first appeared in SCOPe 2.06
  
• d5mrpa_ appears in SCOPe 2.07