SCOPe 2.08: Domain d5u46b_: 5u46 B:

Lineage for d5u46b_ (5u46 B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48527] (37 PDB entries)

8. Domain d5u46b_: 5u46 B: [332211]
   automated match to d2p4ya_
   complexed with 7t1, b7g, peg, pgo

Details for d5u46b_

PDB Entry: 5u46, 2 Å

PDB Description: human ppardelta ligand-binding domain in complexed with gw501516

PDB Compounds: (B:) Peroxisome proliferator-activated receptor delta

SCOPe Domain Sequences for d5u46b_:

Sequence, based on SEQRES records:

>d5u46b_ a.123.1.1 (B:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
pqvadlkafskhiynaylknfnmtkkkarsiltgkashtapfvihdietlwqaekglvwk
qlvnglppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvhea
ifamlasivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdla
lfiaaiilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrql
vtehaqmmqrikktetetslhpllqeiykd

Sequence, based on observed residues (ATOM records):

>d5u46b_ a.123.1.1 (B:) Peroxisome proliferator-activated receptor delta, PPAR-DELTA {Human (Homo sapiens) [TaxId: 9606]}
pqvadlkafskhiynaylknfnmtkkkarsiltapfvihdietlwqaekglvwkqlvngl
ppykeisvhvfyrcqcttvetvreltefaksipsfsslflndqvtllkygvheaifamla
sivnkdgllvangsgfvtreflrslrkpfsdiiepkfefavkfnalelddsdlalfiaai
ilcgdrpglmnvprveaiqdtilralefhlqanhpdaqylfpkllqkmadlrqlvtehaq
mmqrikktetetslhpllqeiykd

Timeline for d5u46b_:

• d5u46b_ first appeared in SCOPe 2.06
  
• d5u46b_ appears in SCOPe 2.07