SCOPe 2.07: Domain d5g2na3: 5g2n A:726-1091

Lineage for d5g2na3 (5g2n A:726-1091)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d5g2na3: 5g2n A:726-1091 [316195]
   Other proteins in same PDB: d5g2na1, d5g2na2, d5g2na4
   automated match to d1he8a4
   complexed with 6e2, so4

Details for d5g2na3

PDB Entry: 5g2n, 2.68 Å

PDB Description: x-ray structure of pi3kinase gamma in complex with copanlisib

PDB Compounds: (A:) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d5g2na3:

Sequence, based on SEQRES records:

>d5g2na3 d.144.1.0 (A:726-1091) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrv
pydpglkagalaiekckvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlil
qilrimesiwetesldlcllpygcistgdkigmieivkdattiakiqqstvgntgafkde
vlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndnimitetgnlfhidf
ghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtn
lliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfn
wflhlv

Sequence, based on observed residues (ATOM records):

>d5g2na3 d.144.1.0 (A:726-1091) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrv
pydpglkagalaiekckvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlil
qilrimesiwetesldlcllpygcistgdkigmieivkdattiakiqtgafkdevlnhwl
kekspteekfqaaverfvyscagycvatfvlgigdrhndnimitetgnlfhidfghierv
pfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpdie
yirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlv

Timeline for d5g2na3:

• d5g2na3 first appeared in SCOPe 2.06
  
• d5g2na3 appears in the current release, SCOPe 2.08