SCOPe 2.06: Domain d5fdod1: 5fdo D:172-320

Lineage for d5fdod1 (5fdo D:172-320)

1. Root: SCOPe 2.06

2. Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein automated matches [190236] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188722] (49 PDB entries)

8. Domain d5fdod1: 5fdo D:172-320 [314083]
   Other proteins in same PDB: d5fdoa2, d5fdob2, d5fdoc2, d5fdod2
   automated match to d2kbwa_
   complexed with 5x2

Details for d5fdod1

PDB Entry: 5fdo, 2.8 Å

PDB Description: mcl-1 complexed with small molecule inhibitor

PDB Compounds: (D:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d5fdod1:

Sequence, based on SEQRES records:

>d5fdod1 f.1.4.1 (D:172-320) automated matches {Human (Homo sapiens) [TaxId: 9606]}
delyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffh

Sequence, based on observed residues (ATOM records):

>d5fdod1 f.1.4.1 (D:172-320) automated matches {Human (Homo sapiens) [TaxId: 9606]}
delyrqsleiisrylreqatgatsrkaletlrrvgdgvqrnhetafqgmlrkldiknedd
vkslsrvmihvfsvtnwgrivtlisfgafvakhlktinqescieplaesitdvlvrtkrd
wlvkqrgwdgfveffh

Timeline for d5fdod1:

• d5fdod1 is new in SCOPe 2.06-stable
  
• d5fdod1 appears in SCOPe 2.07
  
• d5fdod1 appears in the current release, SCOPe 2.08