SCOPe 2.06: Domain d5eqea_: 5eqe A:

Lineage for d5eqea_ (5eqe A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.8: Choline kinase [90040] (2 proteins)
   Pfam PF02958

6. Protein Choline kinase [90041] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [311002] (10 PDB entries)

8. Domain d5eqea_: 5eqe A: [310521]
   automated match to d2i7qa_
   complexed with 5r8

Details for d5eqea_

PDB Entry: 5eqe, 2.4 Å

PDB Description: crystal structure of choline kinase alpha-1 bound by [4-[(4-methyl-1, 4-diazepan-1-yl)methyl]phenyl]methanamine (compound 11)

PDB Compounds: (A:) choline kinase alpha

SCOPe Domain Sequences for d5eqea_:

Sequence, based on SEQRES records:

>d5eqea_ d.144.1.8 (A:) Choline kinase {Human (Homo sapiens) [TaxId: 9606]}
deqpeprtrrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgde
prkvllrlygailqmrscnkegseqaqkenefqgaeamvlesvmfailaerslgpklygi
fpqgrleqfipsrrldteelslpdisaeiaekmatfhgmkmpfnkepkwlfgtmekylke
vlrikfteesrikklhkllsynlplelenlrsllestpspvvfchndcqegnilllegre
nsekqklmlidfeyssynyrgfdignhfcewmydysyekypffranirkyptkkqqlhfi
ssylpafqndfenlsteeksiikeemllevnrfalashflwglwsivqakissiefgymd
yaqarfdayfhqkrklgv

Sequence, based on observed residues (ATOM records):

>d5eqea_ d.144.1.8 (A:) Choline kinase {Human (Homo sapiens) [TaxId: 9606]}
deqpeprtrrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgde
prkvllrlygaimvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpdi
saeiaekmatfhgmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlpl
elenlrsllestpspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdig
nhfcewmydysyekypffranirkyptkkqqlhfissylpafqndfenlsteeksiikee
mllevnrfalashflwglwsivqakissiefgymdyaqarfdayfhqkrklgv

Timeline for d5eqea_:

• d5eqea_ is new in SCOPe 2.06-stable
  
• d5eqea_ appears in SCOPe 2.07
  
• d5eqea_ appears in the current release, SCOPe 2.08