SCOP 1.67: Domain d1dira_: 1dir A:

Lineage for d1dira_ (1dir A:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (40 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Dihydropteridin reductase (pteridine reductase) [51769] (6 species)

7. Species Rat (Rattus norvegicus) [TaxId:10116] [51770] (2 PDB entries)

8. Domain d1dira_: 1dir A: [29833]

Details for d1dira_

PDB Entry: 1dir, 2.6 Å

PDB Description: crystal structure of a monoclinic form of dihydropteridine reductase from rat liver

SCOP Domain Sequences for d1dira_:

Sequence; same for both SEQRES and ATOM records:

>d1dira_ c.2.1.2 (A:) Dihydropteridin reductase (pteridine reductase) {Rat (Rattus norvegicus)}
earrvlvyggrgalgsrcvqafrarnwwvasidvveneeasasvivkmtdsfteqadqvt
aevgkllgdqkvdailcvaggwaggnakskslfkncdlmwkqsiwtstisshlatkhlke
gglltlagakaaldgtpgmigygmakgavhqlcqslagknsgmpsgaaaiavlpvtldtp
mnrksmpeadfsswtpleflvetfhdwitgnkrpnsgsliqvvttdgkteltpayf

Timeline for d1dira_:

• d1dira_ first appeared (with stable ids) in SCOP 1.55
  
• d1dira_ appears in SCOP 1.65
  
• d1dira_ appears in SCOP 1.69
  
• d1dira_ appears in the current release, SCOPe 2.08