SCOP 1.73: Domain d1qprf1: 1qpr F:117-285

Lineage for d1qprf1 (1qpr F:117-285)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.17: Nicotinate/Quinolinate PRTase C-terminal domain-like [51690] (2 families)
   incomplete beta/alpha barrel with parallel beta-sheet of 7 strands

5. Family c.1.17.1: NadC C-terminal domain-like [51691] (4 proteins)

6. Protein Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain [51692] (3 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [51694] (4 PDB entries)

8. Domain d1qprf1: 1qpr F:117-285 [29578]
   Other proteins in same PDB: d1qpra2, d1qprb2, d1qprc2, d1qprd2, d1qpre2, d1qprf2
   complexed with mw2, o4m, pht, ppc

Details for d1qprf1

PDB Entry: 1qpr, 2.45 Å

PDB Description: quinolinate phosphoribosyltransferase (qaprtase) from mycobacterium tuberculosis in complex with phthalate and prpcp

PDB Compounds: (F:) quinolinic acid phosphoribosyltransferase

SCOP Domain Sequences for d1qprf1:

Sequence; same for both SEQRES and ATOM records:

>d1qprf1 c.1.17.1 (F:117-285) Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain {Mycobacterium tuberculosis [TaxId: 1773]}
iatataawvdavrgtkakirdtrktlpglralqkyavrtgggvnhrlglgdaalikdnhv
aaagsvvdalravrnaapdlpcevevdsleqldavlpekpelilldnfavwqtqtavqrr
dsraptvmlessgglslqtaatyaetgvdylavgalthsvrvldigldm

Timeline for d1qprf1:

• d1qprf1 first appeared (with stable ids) in SCOP 1.55
  
• d1qprf1 appears in SCOP 1.71
  
• d1qprf1 appears in SCOP 1.75
  
• d1qprf1 appears in the current release, SCOPe 2.08