SCOPe 2.08: Domain d3tl5a5: 3tl5 A:143-143

Lineage for d3tl5a5 (3tl5 A:143-143)

1. Root: SCOPe 2.08

2. Class l: Artifacts [310555] (1 fold)

3. Fold l.1: Tags [310573] (1 superfamily)

4. Superfamily l.1.1: Tags [310607] (1 family)

5. Family l.1.1.1: Tags [310682] (2 proteins)

6. Protein N-terminal Tags [310894] (1 species)

7. Species Synthetic [311501] (15360 PDB entries)

8. Domain d3tl5a5: 3tl5 A:143-143 [295522]
   Other proteins in same PDB: d3tl5a1, d3tl5a2, d3tl5a3, d3tl5a4
   complexed with 980

Details for d3tl5a5

PDB Entry: 3tl5, 2.79 Å

PDB Description: Discovery of GDC-0980: a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor for the Treatment of Cancer

PDB Compounds: (A:) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d3tl5a5:

Sequence; same for both SEQRES and ATOM records:

>d3tl5a5 l.1.1.1 (A:143-143) N-terminal Tags {Synthetic}
m

Timeline for d3tl5a5:

• d3tl5a5 first appeared in SCOPe 2.06
  
• d3tl5a5 appears in SCOPe 2.07