SCOP 1.69: Domain d2tsya_: 2tsy A:

Lineage for d2tsya_ (2tsy A:)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (31 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (4 families)

5. Family c.1.2.4: Tryptophan biosynthesis enzymes [51381] (3 proteins)

6. Protein Trp synthase alpha-subunit [51388] (3 species)

7. Species Salmonella typhimurium [TaxId:90371] [51389] (33 PDB entries)

8. Domain d2tsya_: 2tsy A: [28583]
   Other proteins in same PDB: d2tsyb_

Details for d2tsya_

PDB Entry: 2tsy, 2.5 Å

PDB Description: crystal structures of mutant (betak87t) tryptophan synthase alpha2 beta2 complex with ligands bound to the active sites of the alpha and beta subunits reveal ligand-induced conformational changes

SCOP Domain Sequences for d2tsya_:

Sequence; same for both SEQRES and ATOM records:

>d2tsya_ c.1.2.4 (A:) Trp synthase alpha-subunit {Salmonella typhimurium}
meryenlfaqlndrregafvpfvtlgdpgieqslkiidtlidagadalelgvpfsdplad
gptiqnanlrafaagvtpaqcfemlalirekhptipigllmyanlvfnngidafyarceq
vgvdsvlvadvpveesapfrqaalrhniapificppnadddllrqvasygrgytyllsrs
gvtgaenhhlieklkeyhaapalqgfgisspeqvsaavragaagaisgsaivkiieknla
spkqmlaelrsfvsamkaasra

Timeline for d2tsya_:

• d2tsya_ first appeared (with stable ids) in SCOP 1.55
  
• d2tsya_ appears in SCOP 1.67
  
• d2tsya_ appears in SCOP 1.71
  
• d2tsya_ appears in the current release, SCOPe 2.08