SCOPe 2.07: Domain d4tlsa_: 4tls A:

Lineage for d4tlsa_ (4tls A:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.3: Prealbumin-like [49451] (8 superfamilies)
   sandwich; 7 strands in 2 sheets, greek-key
   variations: some members have additional 1-2 strands to common fold

4. Superfamily b.3.4: Transthyretin (synonym: prealbumin) [49472] (2 families)

5. Family b.3.4.1: Transthyretin (synonym: prealbumin) [49473] (2 proteins)
   automatically mapped to Pfam PF00576

6. Protein Transthyretin (synonym: prealbumin) [49474] (5 species)
   sandwich; 8 strands in 2 sheets

7. Species Human (Homo sapiens) [TaxId:9606] [49475] (320 PDB entries)
   Uniprot P02766 31-143

8. Domain d4tlsa_: 4tls A: [278417]
   automated match to d2roya_
   complexed with gol, na, po4; mutant

Details for d4tlsa_

PDB Entry: 4tls, 1.35 Å

PDB Description: crystal structure of human transthyretin glu92pro mutant

PDB Compounds: (A:) Transthyretin

SCOPe Domain Sequences for d4tlsa_:

Sequence; same for both SEQRES and ATOM records:

>d4tlsa_ b.3.4.1 (A:) Transthyretin (synonym: prealbumin) {Human (Homo sapiens) [TaxId: 9606]}
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehapvvftandsgprrytiaallspysysttavvtn

Timeline for d4tlsa_:

• d4tlsa_ first appeared in SCOPe 2.05
  
• d4tlsa_ appears in SCOPe 2.06
  
• d4tlsa_ appears in the current release, SCOPe 2.08