SCOPe 2.08: Domain d5a4ca_: 5a4c A:

Lineage for d5a4ca_ (5a4c A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (47 PDB entries)

8. Domain d5a4ca_: 5a4c A: [275544]
   Other proteins in same PDB: d5a4cb2
   automated match to d4v04b_
   complexed with edo, so4, xoj

Details for d5a4ca_

PDB Entry: 5a4c, 2.09 Å

PDB Description: fgfr1 ligand complex

PDB Compounds: (A:) fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, pfeiffer syndrome), isoform cra_b

SCOPe Domain Sequences for d5a4ca_:

Sequence, based on SEQRES records:

>d5a4ca_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgley
synpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfg
lardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypg
vpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsn
qe

Sequence, based on observed residues (ATOM records):

>d5a4ca_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
elpedprwelprdrlvlgkplgefgqvvlaeaigldkdkpnrvtkvavkmlksdatekdl
sdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppgleysy
npshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfgli
dyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfk
llkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsnqe

Timeline for d5a4ca_:

• d5a4ca_ first appeared in SCOPe 2.05
  
• d5a4ca_ appears in SCOPe 2.07