SCOPe 2.08: Domain d5a4cb1: 5a4c B:461-765

Lineage for d5a4cb1 (5a4c B:461-765)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (47 PDB entries)

8. Domain d5a4cb1: 5a4c B:461-765 [275542]
   Other proteins in same PDB: d5a4cb2
   automated match to d4v04b_
   complexed with edo, so4, xoj

Details for d5a4cb1

PDB Entry: 5a4c, 2.09 Å

PDB Description: fgfr1 ligand complex

PDB Compounds: (B:) fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, pfeiffer syndrome), isoform cra_b

SCOPe Domain Sequences for d5a4cb1:

Sequence, based on SEQRES records:

>d5a4cb1 d.144.1.7 (B:461-765) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
seyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksda
tekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppg
leysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkia
dfglardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggsp
ypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrival
tsnqe

Sequence, based on observed residues (ATOM records):

>d5a4cb1 d.144.1.7 (B:461-765) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
seyelpedprwelprdrlvlgkplgegafgqvvlaeaigldpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppeqls
skdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfglaidyykkttngr
lpvkwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdk
psnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsnqe

Timeline for d5a4cb1:

• d5a4cb1 first appeared in SCOPe 2.05, called d5a4cb_
  
• d5a4cb1 appears in SCOPe 2.07