SCOPe 2.07: Domain d4oraa_: 4ora A:

Lineage for d4oraa_ (4ora A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.159: Metallo-dependent phosphatases [56299] (1 superfamily)
   4 layers: alpha/beta/beta/alpha; mixed beta sheets; contains duplication

4. Superfamily d.159.1: Metallo-dependent phosphatases [56300] (13 families)
   different families of this superfamily are groupped in a single Pfam family, Pfam PF00149

5. Family d.159.1.3: Protein serine/threonine phosphatase [56310] (6 proteins)

6. Protein automated matches [190344] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187171] (11 PDB entries)

8. Domain d4oraa_: 4ora A: [272882]
   Other proteins in same PDB: d4orab_
   automated match to d1auia_
   complexed with ca, fe, zn; mutant

Details for d4oraa_

PDB Entry: 4ora, 2.75 Å

PDB Description: crystal structure of a human calcineurin mutant

PDB Compounds: (A:) Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

SCOPe Domain Sequences for d4oraa_:

Sequence, based on SEQRES records:

>d4oraa_ d.159.1.3 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pppppppgadrvvkavpfppthrltseevfdldgiprvdvlknhlvkegrvdeeialrii
negaailrrektmieveapitvcgdihgqffdlmklfevggspantrylflgdyvdrgyf
siecvlylwvlkilypstlfllrgnhecrhlteyftfkqeckikyservyeacmeafdsl
plaallnqqflcvhgglspeihtlddirrldrfkeppafgpmcdllwsdpsedfgneksq
ehfshntvrgcsyfynypavceflqnnnllsiiraheaqdagyrmyrksqttgfpsliti
fsapnyldvynnkaavlkyennvmnirqfncsphpywlpnfmdvftwslpfvgekvteml
vnvlsicsddelmtegedqfdgsaaarkeiirnkiraigkmarylsvlreesesvltlkg
ltptgmlpsgvlaggrqtlqsatveaieaekairgfspphricsfeeakgldrinermpp
r

Sequence, based on observed residues (ATOM records):

>d4oraa_ d.159.1.3 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pppppppgadrvvkavpfppthrltseevfdldgiprvdvlknhlvkegrvdeeialrii
negaailrrektmieveapitvcgdihgqffdlmklfevggspantrylflgdyvdrgyf
siecvlylwvlkilypstlfllrgnhecrhlteyftfkqeckikyservyeacmeafdsl
plaallnqqflcvhgglspeihtlddirrldrfkeppafgpmcdllwsdpsedfgneksq
ehfshntvrgcsyfynypavceflqnnnllsiiraheaqdagyrmyrksqttgfpsliti
fsapnyldvynnkaavlkyennvmnirqfncsphpywlpnfmdvftwslpfvgekvteml
vnvlsicsddelarylsvlsfeeakgldrinermppr

Timeline for d4oraa_:

• d4oraa_ first appeared in SCOPe 2.05
  
• d4oraa_ appears in SCOPe 2.06
  
• d4oraa_ appears in the current release, SCOPe 2.08