SCOPe 2.06: Domain d4xeyb2: 4xey B:251-523

Lineage for d4xeyb2 (4xey B:251-523)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)

8. Domain d4xeyb2: 4xey B:251-523 [271087]
   Other proteins in same PDB: d4xeyb1
   automated match to d1opka3
   complexed with 1n1

Details for d4xeyb2

PDB Entry: 4xey, 2.89 Å

PDB Description: crystal structure of an sh2-kinase domain construct of c-abl tyrosine kinase

PDB Compounds: (B:) Tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d4xeyb2:

Sequence, based on SEQRES records:

>d4xeyb2 d.144.1.7 (B:251-523) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavmk
eikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissam
eylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapesl
aynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyel
mracwqwnpsdrpsfaeihqafetmfqessisd

Sequence, based on observed residues (ATOM records):

>d4xeyb2 d.144.1.7 (B:251-523) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ydkwemertditmkhklevyegvwkkysltvavktltmeveeflkeaavmkeikhpnlvq
llgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissameylekknfi
hrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslaynkfsiks
dvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmracwqwnp
sdrpsfaeihqafetmfqessisd

Timeline for d4xeyb2:

• d4xeyb2 first appeared in SCOPe 2.05
  
• d4xeyb2 appears in SCOPe 2.07
  
• d4xeyb2 appears in the current release, SCOPe 2.08