Lineage for d4wr8a_ (4wr8 A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2202456Fold d.80: Tautomerase/MIF [55330] (1 superfamily)
    (beta-alpha-beta)2; 2 layers: alpha/beta; mixed beta-sheet
    generally forms trimers with three closely packed beta-sheets
  4. 2202457Superfamily d.80.1: Tautomerase/MIF [55331] (7 families) (S)
  5. 2202651Family d.80.1.3: MIF-related [55339] (2 proteins)
    automatically mapped to Pfam PF01187
  6. 2202668Protein Microphage migration inhibition factor (MIF) [55340] (7 species)
    synonym: glycosylation-inhibiting factor (GIF)
  7. 2202674Species Human (Homo sapiens) [TaxId:9606] [55341] (71 PDB entries)
  8. 2202901Domain d4wr8a_: 4wr8 A: [269993]
    automated match to d1ljta_
    complexed with 3tx, na, so4

Details for d4wr8a_

PDB Entry: 4wr8 (more details), 2.6 Å

PDB Description: macrophage migration inhibitory factor in complex with a biaryltriazole inhibitor (3b-180)
PDB Compounds: (A:) macrophage migration inhibitory factor

SCOPe Domain Sequences for d4wr8a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4wr8a_ d.80.1.3 (A:) Microphage migration inhibition factor (MIF) {Human (Homo sapiens) [TaxId: 9606]}
pmfivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa

SCOPe Domain Coordinates for d4wr8a_:

Click to download the PDB-style file with coordinates for d4wr8a_.
(The format of our PDB-style files is described here.)

Timeline for d4wr8a_: