Lineage for d4cmta_ (4cmt A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2984752Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2984753Protein automated matches [190417] (37 species)
    not a true protein
  7. 2984910Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)
  8. 2985259Domain d4cmta_: 4cmt A: [266000]
    automated match to d4foda_
    complexed with gwh

Details for d4cmta_

PDB Entry: 4cmt (more details), 1.73 Å

PDB Description: structure of the human anaplastic lymphoma kinase in complex with the inhibitor 3-((1r)-1-(5-fluoro-2-(2h-1,2,3-triazol-2-yl)phenyl) ethoxy)- 5-(3-(methylsulfonyl)phenyl)pyridin-2-amine
PDB Compounds: (A:) ALK tyrosine kinase receptor

SCOPe Domain Sequences for d4cmta_:

Sequence, based on SEQRES records: (download)

>d4cmta_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npnycfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsplqvavktl
pevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretr
prpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfg
mardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympyps
ksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdv
intalpiey

Sequence, based on observed residues (ATOM records): (download)

>d4cmta_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npnycfagktssisdlkevprknitlirglghgevyegqvsplqvavktlpevcseqdel
dflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpsqslaml
dllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmardiyramlpv
kwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkn
cpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpiey

SCOPe Domain Coordinates for d4cmta_:

Click to download the PDB-style file with coordinates for d4cmta_.
(The format of our PDB-style files is described here.)

Timeline for d4cmta_: