Lineage for d4foda_ (4fod A:)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. Protein automated matches [190417] (36 species)
    not a true protein
  7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1454 PDB entries)
  8. Domain d4foda_: 4fod A: [221392]
    automated match to d2i0ya_
    complexed with 0uv, gol

Details for d4foda_

PDB Entry: 4fod (more details), 2 Å

PDB Description: crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 36
PDB Compounds: (A:) ALK tyrosine kinase receptor

SCOPe Domain Sequences for d4foda_:

Sequence, based on SEQRES records: (download)

>d4foda_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tstimtdynpnysfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsp
lqvavktlpevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdl
ksflretrprpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgr
vakigdfgmardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifs
lgympypsksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerie
yctqdpdvintalpieygplv

Sequence, based on observed residues (ATOM records): (download)

>d4foda_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tstimtdynpnysfagktssisdlkevprknitlirglghgafgevyegqvssplqvavk
tlpevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflre
trprpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigd
fgmardiyracamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqe
vlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintal
pieygplv

SCOPe Domain Coordinates for d4foda_ are not available.

Timeline for d4foda_: