Lineage for d4wunb_ (4wun B:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1930369Protein Fibroblast growth factor receptor 1 [56158] (1 species)
    PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase
  7. 1930370Species Human (Homo sapiens) [TaxId:9606] [56159] (29 PDB entries)
  8. 1930372Domain d4wunb_: 4wun B: [261202]
    automated match to d4nkab_
    complexed with 66t

Details for d4wunb_

PDB Entry: 4wun (more details), 1.65 Å

PDB Description: structure of fgfr1 in complex with azd4547 (n-{3-[2-(3,5- dimethoxyphenyl)ethyl]-1h-pyrazol-5-yl}-4-[(3r,5s)-3,5- dimethylpiperazin-1-yl]benzamide) at 1.65 angstrom
PDB Compounds: (B:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d4wunb_:

Sequence, based on SEQRES records: (download)

>d4wunb_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
seyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksda
tekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppg
leysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkia
dfglardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggsp
ypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrival
ts

Sequence, based on observed residues (ATOM records): (download)

>d4wunb_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
seyelpedprwelprdrlvlgkplgegafgqvvlaeaiglkpnrvtkvavkmlksdatek
dlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppqlss
kdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfgllpvkwmapealfd
riythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdkpsnctnelymmmr
dcwhavpsqrptfkqlvedldrivalts

SCOPe Domain Coordinates for d4wunb_:

Click to download the PDB-style file with coordinates for d4wunb_.
(The format of our PDB-style files is described here.)

Timeline for d4wunb_: