SCOPe 2.05: Domain d4mcda_: 4mcd A:

Lineage for d4mcda_ (4mcd A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.116: alpha/beta knot [75216] (1 superfamily)
   core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot

4. Superfamily c.116.1: alpha/beta knot [75217] (9 families)
   known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
   all known members have dimeric structures

5. Family c.116.1.4: tRNA(m1G37)-methyltransferase TrmD [89629] (2 proteins)
   fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain

6. Protein automated matches [196235] (1 species)
   not a true protein

7. Species Haemophilus influenzae [TaxId:71421] [196236] (7 PDB entries)

8. Domain d4mcda_: 4mcd A: [253783]
   automated match to d1uaja_
   complexed with 22l

Details for d4mcda_

PDB Entry: 4mcd, 1.55 Å

PDB Description: hintrmd in complex with 5-phenylthieno[2,3-d]pyrimidin-4(3h)-one

PDB Compounds: (A:) tRNA (guanine-N(1)-)-methyltransferase

SCOPe Domain Sequences for d4mcda_:

Sequence, based on SEQRES records:

>d4mcda_ c.116.1.4 (A:) automated matches {Haemophilus influenzae [TaxId: 71421]}
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvlgkqasaeedsfadglldcph
ytrpevlegltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkea
qaehns

Sequence, based on observed residues (ATOM records):

>d4mcda_ c.116.1.4 (A:) automated matches {Haemophilus influenzae [TaxId: 71421]}
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvlsfadglldcphytrpevleg
ltvppvlmsghheeirkwrlkqslqrtwlrrpelleglaltdeqrkllkeaqaehns

Timeline for d4mcda_:

• d4mcda_ first appeared in SCOPe 2.04
  
• d4mcda_ appears in SCOPe 2.06
  
• d4mcda_ appears in the current release, SCOPe 2.08