SCOPe 2.05: Domain d4kasc_: 4kas C:

Lineage for d4kasc_ (4kas C:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.207: Thymidylate synthase-complementing protein Thy1 [69795] (1 superfamily)
   complex alpha+beta fold; contains antiparallel 5-stranded beta-sheet: order 12354

4. Superfamily d.207.1: Thymidylate synthase-complementing protein Thy1 [69796] (1 family)
   automatically mapped to Pfam PF02511

5. Family d.207.1.1: Thymidylate synthase-complementing protein Thy1 [69797] (2 proteins)

6. Protein Thy1 homologue [69798] (1 species)

7. Species Thermotoga maritima [TaxId:2336] [69799] (22 PDB entries)
   TM0449

8. Domain d4kasc_: 4kas C: [253226]
   automated match to d4karb_
   complexed with 2pe, cl, du, fad, po4, so4; mutant

Details for d4kasc_

PDB Entry: 4kas, 1.85 Å

PDB Description: Crystal structure of FDTS from T. maritima mutant (H53D) with FAD and dUMP

PDB Compounds: (C:) Thymidylate synthase thyX

SCOPe Domain Sequences for d4kasc_:

Sequence, based on SEQRES records:

>d4kasc_ d.207.1.1 (C:) Thy1 homologue {Thermotoga maritima [TaxId: 2336]}
hmkidildkgfvelvdvmgndlsavraarvsfdmglkdeerdrhlieylmkhgdetpfeh
ivftfhvkapifvarqwfrhriasynelsgrysklsyefyipsperlegykttippervt
ekiseivdkayrtyleliesgvprevarivlplnlytrffwtvnarslmnflnlradsha
qweiqqyalaiarifkekcpwtfeaflkyaykgdilkevqv

Sequence, based on observed residues (ATOM records):

>d4kasc_ d.207.1.1 (C:) Thy1 homologue {Thermotoga maritima [TaxId: 2336]}
hmkidildkgfvelvdvmgndlsavraarvsfdkdeerdrhlieylmkhgdetpfehivf
tfhvkapifvarqwfrhriasynelsgrysklsyefyipsperlegykttippervteki
seivdkayrtyleliesgvprevarivlplnlytrffwtvnarslmnflnlradshaqwe
iqqyalaiarifkekcpwtfeaflkyaykgdilkevqv

Timeline for d4kasc_:

• d4kasc_ first appeared in SCOPe 2.04
  
• d4kasc_ is called d4kasc1 in SCOPe 2.06
  
• d4kasc_ appears in the current release, SCOPe 2.08, called d4kasc1