SCOPe 2.06: Domain d3dyfa_: 3dyf A:

Lineage for d3dyfa_ (3dyf A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.0: automated matches [196408] (1 protein)
   not a true family

6. Protein automated matches [196409] (37 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [230726] (15 PDB entries)

8. Domain d3dyfa_: 3dyf A: [245673]
   automated match to d2ewga_
   complexed with act, bme, ipr, mg, mpd, ni9

Details for d3dyfa_

PDB Entry: 3dyf, 2.65 Å

PDB Description: T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461 and Isopentyl Diphosphate

PDB Compounds: (A:) farnesyl pyrophosphate synthase

SCOPe Domain Sequences for d3dyfa_:

Sequence, based on SEQRES records:

>d3dyfa_ a.128.1.0 (A:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
mpmqmfmqvydeiqmflleelelkfdmdpnrvrylrkmmdttclggkynrgltvidvaes
llslspnnngeeddgarrkrvlhdacvcgwmieflqahylveddimdnsvtrrgkpcwyr
hpdvtvqcaindglllkswthmmamhffadrpflqdllcrfnrvdyttavgqlydvtsmf
dsnkldpdvsqptttdfaeftlsnykrivkyktayytyllplvmglivsealptvdmgvt
eelamlmgeyfqvqddvmdcftpperlgkvgtdiqdakcswlavtflakassaqvaefka
nygsgdsekvatvrrlyeeadlqgdyvayeaavaeqvkelieklrlcspgfaasvetlwg
ktykrqk

Sequence, based on observed residues (ATOM records):

>d3dyfa_ a.128.1.0 (A:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
mpmqmfmqvydeiqmflleelelkfdmdpnrvrylrkmmdttclggkynrgltvidvaes
llsdgarrkrvlhdacvcgwmieflqahylveddimdnsvtrrgkpcwyrhpdvtvqcai
ndglllkswthmmamhffadrpflqdllcrfnrvdyttavgqlydvtsmfdsnkldpdvs
qptttdfaeftlsnykrivkyktayytyllplvmglivsealptvdmgvteelamlmgey
fqvqddvmdcftpperlgkvgtdiqdakcswlavtflakassaqvaefkanygsgdsekv
atvrrlyeeadlqgdyvayeaavaeqvkelieklrlcspgfaasvetlwgktykrqk

Timeline for d3dyfa_:

• d3dyfa_ first appeared in SCOPe 2.04
  
• d3dyfa_ appears in SCOPe 2.05
  
• d3dyfa_ appears in SCOPe 2.07
  
• d3dyfa_ appears in the current release, SCOPe 2.08