SCOPe 2.07: Domain d2ybka_: 2ybk A:

Lineage for d2ybka_ (2ybk A:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
   one turn of helix is made by two pairs of antiparallel strands linked with short turns
   has appearance of a sandwich of distinct architecture and jelly-roll topology

4. Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families)
   Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold

5. Family b.82.2.14: Histone demethylase core [254153] (4 proteins)
   Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801

6. Protein JMJD2A core [254342] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [254775] (57 PDB entries)

8. Domain d2ybka_: 2ybk A: [244720]
   automated match to d4bisa_
   complexed with 2hg, cl, ni, zn

Details for d2ybka_

PDB Entry: 2ybk, 2.4 Å

PDB Description: jmjd2a complexed with r-2-hydroxyglutarate

PDB Compounds: (A:) lysine-specific demethylase 4a

SCOPe Domain Sequences for d2ybka_:

Sequence; same for both SEQRES and ATOM records:

>d2ybka_ b.82.2.14 (A:) JMJD2A core {Human (Homo sapiens) [TaxId: 9606]}
tlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlv
ipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknlt
fnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfa
whtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlis
plmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlc
scrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaeflk

Timeline for d2ybka_:

• d2ybka_ first appeared in SCOPe 2.04
  
• d2ybka_ appears in SCOPe 2.06
  
• d2ybka_ appears in the current release, SCOPe 2.08