SCOPe 2.06: Domain d2vf6a_: 2vf6 A:

Lineage for d2vf6a_ (2vf6 A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.0: automated matches [196408] (1 protein)
   not a true family

6. Protein automated matches [196409] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [231251] (2 PDB entries)

8. Domain d2vf6a_: 2vf6 A: [243865]
   automated match to d2raha_
   complexed with m0n, mg

Details for d2vf6a_

PDB Entry: 2vf6, 2.1 Å

PDB Description: human fdps synthase in complex with minodronate

PDB Compounds: (A:) Farnesyl pyrophosphate synthetase

SCOPe Domain Sequences for d2vf6a_:

Sequence, based on SEQRES records:

>d2vf6a_ a.128.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vyaqekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvvaf
relveprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvglda
indanlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrf
tekryksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldl
fgdpsvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeel
dlpavflqyeedsyshimalieqyaaplppavflglarkiyk

Sequence, based on observed residues (ATOM records):

>d2vf6a_ a.128.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vyaqekqdfvqhfsqivrvltepeigdaiarlkevleynaiggkynrgltvvvafrelve
prkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldaindan
lleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrftekry
ksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldlfgdps
vtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeeldlpav
flqyeedsyshimalieqyaaplppavflglarkiyk

Timeline for d2vf6a_:

• d2vf6a_ first appeared in SCOPe 2.04
  
• d2vf6a_ appears in SCOPe 2.05
  
• d2vf6a_ appears in SCOPe 2.07
  
• d2vf6a_ appears in the current release, SCOPe 2.08