SCOPe 2.05: Domain d4neek_: 4nee K:

Lineage for d4neek_ (4nee K:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.102: Regulatory factor Nef [55670] (1 superfamily)
   alpha(2)-beta(4)-alpha; 3 layers: alpha/beta/alpha

4. Superfamily d.102.1: Regulatory factor Nef [55671] (2 families)

5. Family d.102.1.0: automated matches [191617] (1 protein)
   not a true family

6. Protein automated matches [191127] (2 species)
   not a true protein

7. Species Human immunodeficiency virus 1 [TaxId:11676] [236469] (1 PDB entry)

8. Domain d4neek_: 4nee K: [240623]
   Other proteins in same PDB: d4need_, d4neef_, d4neei_, d4neel_
   automated match to d4neee_

Details for d4neek_

PDB Entry: 4nee, 2.88 Å

PDB Description: crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef

PDB Compounds: (K:) Protein Nef

SCOPe Domain Sequences for d4neek_:

Sequence, based on SEQRES records:

>d4neek_ d.102.1.0 (K:) automated matches {Human immunodeficiency virus 1 [TaxId: 11676]}
xxxxxxxxxxxxxeeevgfpvtpqvplrpmtykaavdlshflkekggleglihsqrrqdi
ldlwiyhtqgyfpdwqnytpgpgvrypltfgwcyklvpvepdkveeankgentsllhpvs
lhgmddperevlewrfdsrlafhhvarelhpeyf

Sequence, based on observed residues (ATOM records):

>d4neek_ d.102.1.0 (K:) automated matches {Human immunodeficiency virus 1 [TaxId: 11676]}
xxxxxxxxxxxxxqvplrpmtykaavdlshflkekggleglihsqrrqdildlwiyhtqg
yfpdwqnytpgpgvrypltfgwcyklvpvepdkveeankgentsllhpvslhgmddpere
vlewrfdsrlafhhvarelhpeyf

Timeline for d4neek_:

• d4neek_ first appeared in SCOPe 2.04
  
• d4neek_ is called d4neek1 in SCOPe 2.06
  
• d4neek_ appears in the current release, SCOPe 2.08, called d4neek1