SCOPe 2.05: Domain d4coha_: 4coh A:

Lineage for d4coha_ (4coh A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (45 species)
   not a true protein

7. Species Trypanosoma cruzi [TaxId:5693] [196511] (10 PDB entries)

8. Domain d4coha_: 4coh A: [238102]
   automated match to d3khma_
   complexed with hem, t9h

Details for d4coha_

PDB Entry: 4coh, 2.08 Å

PDB Description: Crystal structure of Trypanosoma cruzi CYP51 bound to the sulfonamide derivative of the 4-aminopyridyl-based inhibitor

PDB Compounds: (A:) Sterol 14-alpha demethylase

SCOPe Domain Sequences for d4coha_:

Sequence, based on SEQRES records:

>d4coha_ a.104.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
tdppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsrf
fsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhe
vrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmessli
paavfmpwllrlplpqsarcrearaelqkilgeiivarekeeaskdnntsdllggllkav
yrdgtrmslhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaq
lnydnvmdempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshh
deeafpnprlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllr
devpdpdyhtmvvgptlnqclvkytrkkk

Sequence, based on observed residues (ATOM records):

>d4coha_ a.104.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}
tdppvypvtvpflghivqfgknplefmqrckrdlksgvftisiggqrvtivgdphehsrf
fsprneilsprevytimtpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhe
vrkfmaenwkedegvinlledcgamiintacqclfgedlrkrlnarhfaqllskmessli
paavfmpwllrlplpqsarcrearaelqkilgeiivareketsdllggllkavyrdgtrm
slhevcgmivaamfagqhtstittswsmlhlmhpknkkwldklhkeidefpaqlnydnvm
dempfaercvresirrdppllmvmrmvkaevkvgsyvvpkgdiiacspllshhdeeafpn
prlwdperdekvdgafigfgagvhkcigqkfallqvktilatafreydfqllrdevpdpd
yhtmvvgptlnqclvkytrkkk

Timeline for d4coha_:

• d4coha_ first appeared in SCOPe 2.03
  
• d4coha_ appears in SCOPe 2.04
  
• d4coha_ appears in SCOPe 2.06
  
• d4coha_ appears in the current release, SCOPe 2.08