SCOPe 2.05: Domain d4mcba_: 4mcb A:

Lineage for d4mcba_ (4mcb A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.116: alpha/beta knot [75216] (1 superfamily)
   core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot

4. Superfamily c.116.1: alpha/beta knot [75217] (9 families)
   known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
   all known members have dimeric structures

5. Family c.116.1.4: tRNA(m1G37)-methyltransferase TrmD [89629] (2 proteins)
   fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain

6. Protein automated matches [196235] (1 species)
   not a true protein

7. Species Haemophilus influenzae [TaxId:71421] [196236] (7 PDB entries)

8. Domain d4mcba_: 4mcb A: [235592]
   automated match to d4mcca_
   protein/RNA complex; complexed with 21w, act, gol, so4

Details for d4mcba_

PDB Entry: 4mcb, 1.94 Å

PDB Description: h.influenzae trmd in complex with n-(4-{[(1h-imidazol-2-ylmethyl)amino]methyl}benzyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide

PDB Compounds: (A:) tRNA (guanine-N(1)-)-methyltransferase

SCOPe Domain Sequences for d4mcba_:

Sequence, based on SEQRES records:

>d4mcba_ c.116.1.4 (A:) automated matches {Haemophilus influenzae [TaxId: 71421]}
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvlgkqasaeedsfadglldcph
ytrpevlegltvppvlmsghheeirkwrlkqslqrtwlr

Sequence, based on observed residues (ATOM records):

>d4mcba_ c.116.1.4 (A:) automated matches {Haemophilus influenzae [TaxId: 71421]}
mwigvislfpemfkaitefgvtgravkhnllkvecwnprdftfdkhktvddrpygggpgm
lmmvqplrdaihtakaaagegakviylspqgrkldqggvtelaqnqklilvcgryegide
rliqteideewsigdyvltggelpamtlidavarfipgvlglldcphytrpevlegltvp
pvlmshheeirkwrlkqslqrtwlr

Timeline for d4mcba_:

• d4mcba_ first appeared in SCOPe 2.03
  
• d4mcba_ appears in SCOPe 2.04
  
• d4mcba_ appears in SCOPe 2.06
  
• d4mcba_ appears in the current release, SCOPe 2.08