SCOPe 2.07: Domain d4itjb_: 4itj B:

Lineage for d4itjb_ (4itj B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d4itjb_: 4itj B: [234904]
   automated match to d4gt5a_
   complexed with 1hx, iod

Details for d4itjb_

PDB Entry: 4itj, 1.8 Å

PDB Description: Crystal structure of RIP1 kinase in complex with necrostatin-4

PDB Compounds: (B:) Receptor-interacting serine/threonine-protein kinase 1

SCOPe Domain Sequences for d4itjb_:

Sequence, based on SEQRES records:

>d4itjb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lnvikmkssdflesaeldsggfgkvslafhrtqglmimktvykgpnciehnealleeakm
mnrlrhsrvvkllgviieegkyslvmeymekgnlmhvlkaemstplsvkgriileiiegm
aylhgkgvihkdlkpenilvdndfhikiadlglasfkmwsklnneehnelrevdgtakkn
ggtlyymapehlndvnakpteksdvysfavvlwaifankepyenaiaeqqlimaiksgnr
pdvdditeycpreiislmklcweanpearptfpgieekfrpfylsqle

Sequence, based on observed residues (ATOM records):

>d4itjb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lnvikmkssdflesaeldsggfgkvslafhrtqglmimktvykgpnciehnealleeakm
mnrlrhsrvvkllgviieegkyslvmeymekgnlmhvlkaemstplsvkgriileiiegm
aylhgkgvihkdlkpenilvdndfhikiadlglasfkmwsklnneehneltlyymapehl
ndvnakpteksdvysfavvlwaifankepyenaiaeqqlimaiksgnrpdvdditeycpr
eiislmklcweanpearptfpgieekfrpfylsqle

Timeline for d4itjb_:

• d4itjb_ first appeared in SCOPe 2.03
  
• d4itjb_ appears in SCOPe 2.06
  
• d4itjb_ appears in the current release, SCOPe 2.08