SCOPe 2.04: Domain d3zosa_: 3zos A:

Lineage for d3zosa_ (3zos A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (19 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (476 PDB entries)

8. Domain d3zosa_: 3zos A: [233991]
   automated match to d4bkjb_
   complexed with 0li, edo

Details for d3zosa_

PDB Entry: 3zos, 1.92 Å

PDB Description: structure of the ddr1 kinase domain in complex with ponatinib

PDB Compounds: (A:) epithelial discoidin domain-containing receptor 1

SCOPe Domain Sequences for d3zosa_:

Sequence, based on SEQRES records:

>d3zosa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rvdfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilrpda
tknarndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqledk
aaegapgdgqaaqgptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftik
iadfgmsrnlyagdyyrvqgravlpirwmawecilmgkfttasdvwafgvtlwevlmlcr
aqpfgqltdeqvienageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsql
hrflaedalntv

Sequence, based on observed residues (ATOM records):

>d3zosa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rvdfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilrpda
tknarndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqleda
aqgptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikiadfgmsrnly
agdyyrvqgravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraqpfgqltdeq
vienageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhrflaedalnt
v

Timeline for d3zosa_:

• d3zosa_ first appeared in SCOPe 2.03
  
• d3zosa_ appears in SCOPe 2.05
  
• d3zosa_ appears in the current release, SCOPe 2.08