SCOPe 2.05: Domain d4m1ua_: 4m1u A:

Lineage for d4m1ua_ (4m1u A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.165: Ribosome inactivating proteins (RIP) [56370] (1 superfamily)
   contains mixed beta-sheet

4. Superfamily d.165.1: Ribosome inactivating proteins (RIP) [56371] (3 families)

5. Family d.165.1.2: Shiga toxin, A-chain [56395] (2 proteins)

6. Protein Shiga toxin, A-chain [56396] (4 species)

7. Species Escherichia coli [TaxId:83334] [229116] (1 PDB entry)

8. Domain d4m1ua_: 4m1u A: [229117]
   Other proteins in same PDB: d4m1ub_, d4m1uc_, d4m1ud_, d4m1ue_, d4m1uf_
   automated match to d1r4pa_
   complexed with 1ps

Details for d4m1ua_

PDB Entry: 4m1u, 1.56 Å

PDB Description: the crystal structure of stx2 and a disaccharide ligand

PDB Compounds: (A:) Shiga toxin 2 A-subunit

SCOPe Domain Sequences for d4m1ua_:

Sequence, based on SEQRES records:

>d4m1ua_ d.165.1.2 (A:) Shiga toxin, A-chain {Escherichia coli [TaxId: 83334]}
reftidfstqqsyvsslnsirteistplehisqgttsvsvinhtppgsyfavdirgldvy
qarfdhlrliieqnnlyvagfvntatntfyrfsdfthisvpgvttvsmttdssyttlqrv
aalersgmqisrhslvssylalmefsgntmtrdasravlrfvtvtaealrfrqiqrefrq
alsetapvytmtpgdvdltlnwgrisnvlpeyrgedgvrvgrisfnnisailgtvaviln
chhqgarsvravneesqpecqitgdrpvikinntlwesntaaaflnrksqflyttgk

Sequence, based on observed residues (ATOM records):

>d4m1ua_ d.165.1.2 (A:) Shiga toxin, A-chain {Escherichia coli [TaxId: 83334]}
reftidfstqqsyvsslnsirteistplehisqgttsvsvinhtppgsyfavdirgldvy
qarfdhlrliieqnnlyvagfvntatntfyrfsdfthisvpgvttvsmttdssyttlqrv
aalersgmqisrhslvssylalmefsgntmtrdasravlrfvtvtaealrfrqiqrefrq
alsetapvytmtpgdvdltlnwgrisnvlpeyrgedgvrvgrisfnnisailgtvaviln
checqitgdrpvikinntlwesntaaaflnrksqflyttgk

Timeline for d4m1ua_:

• d4m1ua_ first appeared in SCOPe 2.03
  
• d4m1ua_ appears in SCOPe 2.04
  
• d4m1ua_ appears in SCOPe 2.06
  
• d4m1ua_ appears in the current release, SCOPe 2.08