Lineage for d4m6ka_ (4m6k A:)

  1. Root: SCOPe 2.04
  2. 1565955Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1618271Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 1618272Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 1618273Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 1618457Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 1618503Species Human (Homo sapiens) [TaxId:9606] [53607] (61 PDB entries)
  8. 1618524Domain d4m6ka_: 4m6k A: [228386]
    automated match to d1mvta_
    complexed with fol, gol, nap

Details for d4m6ka_

PDB Entry: 4m6k (more details), 1.4 Å

PDB Description: Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and folate
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d4m6ka_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4m6ka_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Human (Homo sapiens) [TaxId: 9606]}
vgslncivavsqnmgigkngdlpwpplrnefryfqrmtttssvegkqnlvimgkktwfsi
peknrplkgrinlvlsrelkeppqgahflsrslddalklteqpelankvdmvwivggssv
ykeamnhpghlklfvtrimqdfesdtffpeidlekykllpeypgvlsdvqeekgikykfe
vyeknd

SCOPe Domain Coordinates for d4m6ka_:

Click to download the PDB-style file with coordinates for d4m6ka_.
(The format of our PDB-style files is described here.)

Timeline for d4m6ka_: