SCOPe 2.08: Domain d4ijqb_: 4ijq B:

Lineage for d4ijqb_ (4ijq B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.61: PRTase-like [53270] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest

4. Superfamily c.61.1: PRTase-like [53271] (3 families)

5. Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (16 proteins)

6. Protein Hypoxanthine-guanine PRTase (HGPRTase) [53283] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53284] (20 PDB entries)

8. Domain d4ijqb_: 4ijq B: [227454]
   automated match to d4ijqd_
   complexed with mg, so4, sv2

Details for d4ijqb_

PDB Entry: 4ijq, 2 Å

PDB Description: Human hypoxanthine-guanine phosphoribosyltransferase in complex with [(2-((Guanine-9H-yl)methyl)propane-1,3-diyl)bis(oxy)]bis(methylene))diphosphonic acid

PDB Compounds: (B:) hypoxanthine-guanine phosphoribosyltransferase

SCOPe Domain Sequences for d4ijqb_:

Sequence, based on SEQRES records:

>d4ijqb_ c.61.1.1 (B:) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}
spgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghhiva
lcvlkggykffadlldyikalnrnsdrsipmtvdfirlksycndqstgdikviggddlst
ltgknvlivediidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeip
dkfvvgyaldyneyfrdlnhvcvisetgkakyka

Sequence, based on observed residues (ATOM records):

>d4ijqb_ c.61.1.1 (B:) Hypoxanthine-guanine PRTase (HGPRTase) {Human (Homo sapiens) [TaxId: 9606]}
spgvvisddepgydldlfcipnhyaedlervfiphglimdrterlardvmkemgghhiva
lcvlkggykffadlldyikalnrnsdrsipmtvdfirlkkviggddlstltgknvlived
iidtgktmqtllslvrqynpkmvkvasllvkrtprsvgykpdfvgfeipdkfvvgyaldy
neyfrdlnhvcvisetgkakyka

Timeline for d4ijqb_:

• d4ijqb_ first appeared in SCOPe 2.03
  
• d4ijqb_ appears in SCOPe 2.07