Lineage for Protein: Hypoxanthine-guanine PRTase (HGPRTase)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2467648Fold c.61: PRTase-like [53270] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
  4. 2467649Superfamily c.61.1: PRTase-like [53271] (3 families) (S)
  5. 2467650Family c.61.1.1: Phosphoribosyltransferases (PRTases) [53272] (16 protein domains)
  6. 2467755Protein Hypoxanthine-guanine PRTase (HGPRTase) [53283] (3 species)

Species:

  1. 2467756Human (Homo sapiens) [TaxId:9606] [53284] (20 PDB entries)
    1. Domains for 1bzy:
      1. 2467765Domain d1bzya_: 1bzy A: [34071]
        complexed with imu, mg, pop
      2. 2467766Domain d1bzyb_: 1bzy B: [34072]
        complexed with imu, mg, pop
      3. 2467767Domain d1bzyc_: 1bzy C: [34073]
        complexed with imu, mg, pop
      4. 2467768Domain d1bzyd_: 1bzy D: [34074]
        complexed with imu, mg, pop
    2. Domains for 1d6n:
      1. 2467826Domain d1d6na_: 1d6n A: [34077]
        complexed with mg, ppo, prp
      2. 2467827Domain d1d6nb_: 1d6n B: [34078]
        complexed with mg, ppo, prp
    3. Domains for 1hmp:
      1. 2467793Domain d1hmpa_: 1hmp A: [34075]
        complexed with 5gp
      2. 2467794Domain d1hmpb_: 1hmp B: [34076]
        complexed with 5gp
    4. Domains for 1z7g:
      1. 2467757Domain d1z7ga_: 1z7g A: [124624]
        automated match to d1bzya_
      2. 2467758Domain d1z7gb_: 1z7g B: [124625]
        automated match to d1bzya_
      3. 2467759Domain d1z7gc_: 1z7g C: [124626]
        automated match to d1bzya_
      4. 2467760Domain d1z7gd_: 1z7g D: [124627]
        automated match to d1bzya_
    5. Domains for 3gep:
      1. 2467795Domain d3gepa_: 3gep A: [176581]
        automated match to d1bzya_
        complexed with 24h
      2. 2467796Domain d3gepb_: 3gep B: [176582]
        automated match to d1bzya_
        complexed with 24h
    6. Domains for 3ggc:
      1. 2467812Domain d3ggca_: 3ggc A: [176619]
        automated match to d1bzya_
        complexed with h26
      2. 2467813Domain d3ggcb_: 3ggc B: [176620]
        automated match to d1bzya_
        complexed with h26
    7. Domains for 3ggj:
      1. 2467809Domain d3ggja_: 3ggj A: [176621]
        automated match to d1bzya_
        complexed with 25h
      2. 2467810Domain d3ggjb_: 3ggj B: [176622]
        automated match to d1bzya_
        complexed with 25h
    8. Domains for 4ijq:
      1. 2467761Domain d4ijqa_: 4ijq A: [227453]
        automated match to d4ijqd_
        complexed with mg, so4, sv2
      2. 2467762Domain d4ijqb_: 4ijq B: [227454]
        automated match to d4ijqd_
        complexed with mg, so4, sv2
      3. 2467763Domain d4ijqc_: 4ijq C: [227455]
        automated match to d4ijqd_
        complexed with mg, so4, sv2
      4. 2467764Domain d4ijqd_: 4ijq D: [196727]
        automated match to d3gepa_
        complexed with mg, so4, sv2
    9. Domain for 4kn6:
    10. Domains for 4rab:
      1. 2467797Domain d4raba_: 4rab A: [280057]
        automated match to d3gepa_
        complexed with 3l3, mg, po4
      2. 2467798Domain d4rabb_: 4rab B: [280055]
        automated match to d3gepa_
        complexed with 3l3, mg, po4
      3. 2467799Domain d4rabc_: 4rab C: [280054]
        automated match to d3gepa_
        complexed with 3l3, mg, po4
      4. 2467800Domain d4rabd_: 4rab D: [280059]
        automated match to d3gepa_
        complexed with 3l3, mg, po4
    11. Domains for 4rac:
      1. 2467789Domain d4raca_: 4rac A: [280046]
        automated match to d3gepa_
        complexed with 3l4, mg
      2. 2467790Domain d4racb_: 4rac B: [280049]
        automated match to d3gepa_
        complexed with 3l4, mg
      3. 2467791Domain d4racc_: 4rac C: [280053]
        automated match to d3gepa_
        complexed with 3l4, mg
      4. 2467792Domain d4racd_: 4rac D: [280047]
        automated match to d3gepa_
        complexed with 3l4, mg
    12. Domains for 4rad:
      1. 2467781Domain d4rada_: 4rad A: [280062]
        automated match to d3gepa_
        complexed with 3l5, mg
      2. 2467782Domain d4radb_: 4rad B: [280064]
        automated match to d3gepa_
        complexed with 3l5, mg
      3. 2467783Domain d4radc_: 4rad C: [280067]
        automated match to d3gepa_
        complexed with 3l5, mg
      4. 2467784Domain d4radd_: 4rad D: [280069]
        automated match to d3gepa_
        complexed with 3l5, mg
      5. 2467785Domain d4rade_: 4rad E: [280065]
        automated match to d3gepa_
        complexed with 3l5, mg
      6. 2467786Domain d4radf_: 4rad F: [280066]
        automated match to d3gepa_
        complexed with 3l5, mg
      7. 2467787Domain d4radg_: 4rad G: [280070]
        automated match to d3gepa_
        complexed with 3l5, mg
      8. 2467788Domain d4radh_: 4rad H: [280068]
        automated match to d3gepa_
        complexed with 3l5, mg
    13. Domains for 4ran:
      1. 2467814Domain d4rana_: 4ran A: [280043]
        automated match to d3gepa_
        complexed with 3l6, mg
      2. 2467815Domain d4ranb_: 4ran B: [280050]
        automated match to d3gepa_
        complexed with 3l6, mg
      3. 2467816Domain d4ranc_: 4ran C: [280044]
        automated match to d3gepa_
        complexed with 3l6, mg
      4. 2467817Domain d4rand_: 4ran D: [280058]
        automated match to d3gepa_
        complexed with 3l6, mg
    14. Domains for 4rao:
      1. 2467773Domain d4raoa_: 4rao A: [280056]
        automated match to d3gepa_
        complexed with 3l7, mg
      2. 2467774Domain d4raob_: 4rao B: [280061]
        automated match to d3gepa_
        complexed with 3l7, mg
      3. 2467775Domain d4raoc_: 4rao C: [280060]
        automated match to d3gepa_
        complexed with 3l7, mg
      4. 2467776Domain d4raod_: 4rao D: [280063]
        automated match to d3gepa_
        complexed with 3l7, mg
    15. Domains for 4raq:
      1. 2467818Domain d4raqa_: 4raq A: [280045]
        automated match to d3gepa_
        complexed with 3l8, mg
      2. 2467819Domain d4raqb_: 4raq B: [280051]
        automated match to d3gepa_
        complexed with 3l8, mg
      3. 2467820Domain d4raqc_: 4raq C: [280048]
        automated match to d3gepa_
        complexed with 3l8, mg
      4. 2467821Domain d4raqd_: 4raq D: [280052]
        automated match to d3gepa_
        complexed with 3l8, mg
    16. Domains for 5brn:
      1. 2467801Domain d5brna_: 5brn A: [278016]
        automated match to d3gepa_
        complexed with 4x2, mg
      2. 2467802Domain d5brnb_: 5brn B: [278021]
        automated match to d3gepa_
        complexed with 4x2, mg
      3. 2467803Domain d5brnc_: 5brn C: [278020]
        automated match to d3gepa_
        complexed with 4x2, mg
      4. 2467804Domain d5brnd_: 5brn D: [278018]
        automated match to d3gepa_
        complexed with 4x2, mg
    17. Domains for 5bsk:
      1. 2467822Domain d5bska_: 5bsk A: [277079]
        automated match to d3gepa_
        complexed with 4x7, mg
      2. 2467823Domain d5bskb_: 5bsk B: [277078]
        automated match to d3gepa_
        complexed with 4x7, mg
      3. 2467824Domain d5bskc_: 5bsk C: [277077]
        automated match to d3gepa_
        complexed with 4x7, mg
      4. 2467825Domain d5bskd_: 5bsk D: [277076]
        automated match to d3gepa_
        complexed with 4x7, mg
    18. Domains for 5hia:
      1. 2467769Domain d5hiaa_: 5hia A: [328505]
        automated match to d4raoa_
        complexed with mg, ypg
      2. 2467770Domain d5hiab_: 5hia B: [328811]
        automated match to d4raoa_
        complexed with mg, ypg
      3. 2467771Domain d5hiac_: 5hia C: [328805]
        automated match to d4raoa_
        complexed with mg, ypg
      4. 2467772Domain d5hiad_: 5hia D: [328762]
        automated match to d4raoa_
        complexed with mg, ypg
    19. Domains for 5w8v:
      1. 2467805Domain d5w8va1: 5w8v A:4-216 [338770]
        Other proteins in same PDB: d5w8va2
        automated match to d4rade_
        complexed with 9yp, mg
      2. 2467806Domain d5w8vb_: 5w8v B: [338784]
        Other proteins in same PDB: d5w8va2
        automated match to d4rade_
        complexed with 9yp, mg
      3. 2467807Domain d5w8vc_: 5w8v C: [338776]
        Other proteins in same PDB: d5w8va2
        automated match to d4rade_
        complexed with 9yp, mg
      4. 2467808Domain d5w8vd_: 5w8v D: [338798]
        Other proteins in same PDB: d5w8va2
        automated match to d4rade_
        complexed with 9yp, mg
    20. Domains for 6bnj:
      1. 2467777Domain d6bnja_: 6bnj A: [342301]
        automated match to d4raoa_
        complexed with mg, wpg
      2. 2467778Domain d6bnjb_: 6bnj B: [342271]
        automated match to d4raoa_
        complexed with mg, wpg
      3. 2467779Domain d6bnjc_: 6bnj C: [342275]
        automated match to d4raoa_
        complexed with mg, wpg
      4. 2467780Domain d6bnjd_: 6bnj D: [342246]
        automated match to d4raoa_
        complexed with mg, wpg
  2. 2467828Malaria parasite (Plasmodium falciparum) [TaxId:5833] [53285] (1 PDB entry)
  3. 2467833Thermoanaerobacter tengcongensis [TaxId:119072] [117671] (1 PDB entry)
    Uniprot Q8R7L0

More info for Protein Hypoxanthine-guanine PRTase (HGPRTase) from c.61.1.1: Phosphoribosyltransferases (PRTases)

Timeline for Protein Hypoxanthine-guanine PRTase (HGPRTase) from c.61.1.1: Phosphoribosyltransferases (PRTases):