SCOPe 2.03: Domain d3socb_: 3soc B:

Lineage for d3socb_ (3soc B:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (18 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)

8. Domain d3socb_: 3soc B: [216494]
   automated match to d2qlua_
   complexed with edo, gvd

Details for d3socb_

PDB Entry: 3soc, 1.95 Å

PDB Description: Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with a quinazolin

PDB Compounds: (B:) Activin receptor type-2A

SCOPe Domain Sequences for d3socb_:

Sequence, based on SEQRES records:

>d3socb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sgvdlgtenlyfqsmplqllevkargrfgcvwkaqllneyvavkifpiqdkqswqneyev
yslpgmkhenilqfigaekrgtsvdvdlwlitafhekgslsdflkanvvswnelchiaet
marglaylhedipglkdghkpaishrdiksknvllknnltaciadfglalkfeagksagd
thgqvgtrrymapevlegainfqrdaflridmyamglvlwelasrctaadgpvdeymlpf
eeeigqhpsledmqevvvhkkkrpvlrdywqkhagmamlcetieecwdhdaearlsagcv
geritqmqrlt

Sequence, based on observed residues (ATOM records):

>d3socb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sgvdlgtenlyfqsmplqllevkargrfgcvwkaqllneyvavkifpiqdkqswqneyev
yslpgmkhenilqfigaekrgtsvdvdlwlitafhekgslsdflkanvvswnelchiaet
marglaylhedipglkdghkpaishrdiksknvllknnltaciadfglalkfeagksath
gqvgtrrymapevlegainfqrdaflridmyamglvlwelasrctaadgpvdeymlpfee
eigqhpsledmqevvvhkkkrpvlrdywqkhagmamlcetieecwdhdaearlsagcvge
ritqmqrlt

Timeline for d3socb_:

• d3socb_ is new in SCOPe 2.03-stable
  
• d3socb_ appears in SCOPe 2.04
  
• d3socb_ appears in the current release, SCOPe 2.08, called d3socb1