SCOPe 2.04: Domain d3nlia_: 3nli A:

Lineage for d3nlia_ (3nli A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein automated matches [190421] (5 species)
   not a true protein

7. Species Cow (Bos taurus) [TaxId:9913] [188827] (15 PDB entries)

8. Domain d3nlia_: 3nli A: [214006]
   automated match to d3hsnb_
   complexed with act, cad, gol, h4b, hem, jrr, zn; mutant

Details for d3nlia_

PDB Entry: 3nli, 1.98 Å

PDB Description: structure of endothelial nitric oxide synthase n368d mutant heme domain complexed with 6-{{(3'r,4'r)-3'-[2"-(3'''- fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin- 2-amine

PDB Compounds: (A:) Nitric oxide synthase, endothelial

SCOPe Domain Sequences for d3nlia_:

Sequence, based on SEQRES records:

>d3nlia_ d.174.1.1 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}
gpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprklqtrpspgpppaeqll
sqardfinqyyssikrsgsqaheerlqeveaevastgtyhlreselvfgakqawrnaprc
vgriqwgklqvfdardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriw
nsqlvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfv
lppelvlevplehptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigt
rdlcdphryniledvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaat
vsfmkhldneqkarggcpadwawivppisgsltpvfhqemvnyilspafryqpdpw

Sequence, based on observed residues (ATOM records):

>d3nlia_ d.174.1.1 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}
gpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlpraeqllsqardfinqyys
sikrsgsqaheerlqeveaevastgtyhlreselvfgakqawrnaprcvgriqwgklqvf
dardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriwnsqlvryagyrq
qdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfvlppelvlevple
hptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigtrdlcdphrynil
edvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaatvsfmkhldneqk
arggcpadwawivppisgsltpvfhqemvnyilspafryqpdpw

Timeline for d3nlia_:

• d3nlia_ first appeared in SCOPe 2.03
  
• d3nlia_ appears in SCOPe 2.05
  
• d3nlia_ appears in the current release, SCOPe 2.08