SCOPe 2.08: Domain d2hrpm2: 2hrp M:108-214

Lineage for d2hrpm2 (2hrp M:108-214)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (374 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d2hrpm2: 2hrp M:108-214 [21196]
   Other proteins in same PDB: d2hrph1, d2hrph2, d2hrpl1, d2hrpm1, d2hrpn1, d2hrpn2
   part of Fab F11.2.32 against HIV-1 protease

Details for d2hrpm2

PDB Entry: 2hrp, 2.2 Å

PDB Description: antigen-antibody complex

PDB Compounds: (M:) monoclonal antibody f11.2.32

SCOPe Domain Sequences for d2hrpm2:

Sequence; same for both SEQRES and ATOM records:

>d2hrpm2 b.1.1.2 (M:108-214) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnrnec

Timeline for d2hrpm2:

• d2hrpm2 first appeared (with stable ids) in SCOP 1.55
  
• d2hrpm2 appears in SCOPe 2.07