SCOPe 2.07: Domain d3e34a_: 3e34 A:

Lineage for d3e34a_ (3e34 A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.6: Protein prenylyltransferase [48439] (2 families)

5. Family a.118.6.1: Protein prenylyltransferase [48440] (3 proteins)

6. Protein Protein farnesyltransferase alpha-subunit [48441] (2 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [48442] (51 PDB entries)
   Uniprot Q04631 55-369

8. Domain d3e34a_: 3e34 A: [209381]
   Other proteins in same PDB: d3e34b_
   automated match to d1d8da_
   complexed with ed1, fpp, zn

Details for d3e34a_

PDB Entry: 3e34, 2.05 Å

PDB Description: Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10

PDB Compounds: (A:) Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

SCOPe Domain Sequences for d3e34a_:

Sequence; same for both SEQRES and ATOM records:

>d3e34a_ a.118.6.1 (A:) Protein farnesyltransferase alpha-subunit {Norway rat (Rattus norvegicus) [TaxId: 10116]}
flsldsptyvlyrdraewadidpvpqndgpspvvqiiysekfrdvydyfravlqrderse
rafkltrdaielnaanytvwhfrrvllrslqkdlqeemnyiiaiieeqpknyqvwhhrrv
lvewlkdpsqelefiadilnqdaknyhawqhrqwviqefrlwdnelqyvdqllkedvrnn
svwnqrhfvisnttgysdravlerevqytlemiklvphnesawnylkgilqdrglsrypn
llnqlldlqpshsspyliaflvdiyedmlenqcdnkedilnkalelceilakekdtirke
ywryigrslqskhsresdipasv

Timeline for d3e34a_:

• d3e34a_ first appeared in SCOPe 2.03
  
• d3e34a_ appears in SCOPe 2.06
  
• d3e34a_ appears in the current release, SCOPe 2.08