SCOPe 2.08: Domain d4b8wb1: 4b8w B:-1-317

Lineage for d4b8wb1 (4b8w B:-1-317)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (319 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186944] (65 PDB entries)

8. Domain d4b8wb1: 4b8w B:-1-317 [201581]
   Other proteins in same PDB: d4b8wa2, d4b8wb2
   automated match to d4b8wa_
   complexed with gdp, nap

Details for d4b8wb1

PDB Entry: 4b8w, 2.75 Å

PDB Description: crystal structure of human gdp-l-fucose synthase with bound nadp and gdp, tetragonal crystal form

PDB Compounds: (B:) GDP-l-fucose synthase

SCOPe Domain Sequences for d4b8wb1:

Sequence, based on SEQRES records:

>d4b8wb1 c.2.1.0 (B:-1-317) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smrilvtggsglvgkaiqkvvadgaglpgedwvfvsskdadltdtaqtralfekvqpthv
ihlaamvgglfrnikynldfwrknvhmndnvlhsafevgarkvvsclstcifpdkttypi
detmihngpphnsnfgysyakrmidvqnrayfqqygctftaviptnvfgphdnfniedgh
vlpglihkvhlakssgsaltvwgtgnprrqfiysldlaqlfiwvlreynevepiilsvge
edevsikeaaeavveamdfhgevtfdttksdgqfkktasnsklrtylpdfrftpfkqavk
etcawftdnye

Sequence, based on observed residues (ATOM records):

>d4b8wb1 c.2.1.0 (B:-1-317) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smrilvtggsglvgkaiqkvvapgedwvfvsskdadltdtaqtralfekvqpthvihlaa
mvnldfwrknvhmndnvlhsafevgarkvvsclstcifpdkttypidetmihngpphnsn
fgysyakrmidvqnrayfqqygctftaviptnvfgphdnfniedghvlpglihkvhlaks
sgsaltvwgtgnprrqfiysldlaqlfiwvlreynevepiilsvgeedevsikeaaeavv
eamdfhgevtfdttksdgqfkktasnsklrtylpdfrftpfkqavketcawftdnye

Timeline for d4b8wb1:

• d4b8wb1 first appeared in SCOPe 2.03, called d4b8wb_
  
• d4b8wb1 appears in SCOPe 2.07