SCOPe 2.08: Domain d4apua_: 4apu A:

Lineage for d4apua_ (4apu A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (171 PDB entries)

8. Domain d4apua_: 4apu A: [201471]
   automated match to d2w8ya_
   complexed with a2k, or8, so4

Details for d4apua_

PDB Entry: 4apu, 1.9 Å

PDB Description: pr x-ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids

PDB Compounds: (A:) progesterone receptor

SCOPe Domain Sequences for d4apua_:

Sequence; same for both SEQRES and ATOM records:

>d4apua_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lipplinllmsiepdviyaghdntkpdtssslltslnqlgerqllsvvkwskslpgfrnl
hiddqitliqyswmslmvfglgwrsykhvsgqmlyfapdlilneqrmkessfyslcltmw
qipqefvklqvsqeeflcmkvllllntipleglrsqtqfeemrssyirelikaiglrqkg
vvsssqrfyqltklldnlhdlvkqlhlyclntfiqsralsvefpemmseviaaqlpkila
gmvkpllfhk

Timeline for d4apua_:

• d4apua_ first appeared in SCOPe 2.03
  
• d4apua_ appears in SCOPe 2.07