SCOP 1.69: Domain d1vfaa_: 1vfa A:

Lineage for d1vfaa_ (1vfa A:)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (162 PDB entries)

8. Domain d1vfaa_: 1vfa A: [19928]
   Other proteins in same PDB: d1vfab_
   part of Fv D1.3

Details for d1vfaa_

PDB Entry: 1vfa, 1.8 Å

PDB Description: bound water molecules and conformational stabilization help mediate an antigen-antibody association

SCOP Domain Sequences for d1vfaa_:

Sequence; same for both SEQRES and ATOM records:

>d1vfaa_ b.1.1.1 (A:) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4}
divltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvyytttladgvps
rfsgsgsgtqyslkinslqpedfgsyycqhfwstprtfgggtkleikr

Timeline for d1vfaa_:

• d1vfaa_ first appeared (with stable ids) in SCOP 1.55
  
• d1vfaa_ appears in SCOP 1.67
  
• d1vfaa_ appears in SCOP 1.71
  
• d1vfaa_ appears in the current release, SCOPe 2.08