SCOPe 2.08: Domain d2wkeb_: 2wke B:

Lineage for d2wkeb_ (2wke B:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families)

5. Family e.3.1.3: Dac-like [144040] (3 proteins)
   Pfam PF02113; D-Ala-D-Ala carboxypeptidase 3 (S13) family; contains a large insertion comprising two subdomains: (d1) aplha+beta with topological similarity to one subunit of the DTD-like family (69501) and (d2) six-stranded beta-sandwich with a crossed-loop topology

6. Protein D-alanyl-D-alanine carboxypeptidase Dac [144043] (1 species)

7. Species Actinomadura sp. [TaxId:1989] [144044] (19 PDB entries)
   Uniprot P39045 50-516

8. Domain d2wkeb_: 2wke B: [198514]
   automated match to d2wked_
   complexed with biy, co, so4

Details for d2wkeb_

PDB Entry: 2wke, 2.2 Å

PDB Description: crystal structure of the actinomadura r39 dd-peptidase inhibited by 6-beta-iodopenicillanate.

PDB Compounds: (B:) d-alanyl-d-alanine carboxypeptidase

SCOPe Domain Sequences for d2wkeb_:

Sequence; same for both SEQRES and ATOM records:

>d2wkeb_ e.3.1.3 (B:) D-alanyl-D-alanine carboxypeptidase Dac {Actinomadura sp. [TaxId: 1989]}
rltelredidailedpalegavsgvvvvdtatgeelysrdggeqllpasnmklftaaaal
evlgadhsfgtevaaesapgrrgevqdlylvgrgdptlsaedldamaaevaasgvrtvrg
dlyaddtwfdserlvddwwpedepyaysaqisaltvahgerfdtgvtevsvtpaaegepa
dvdlgaaegyaeldnravtgaagsantlvidrpvgtntiavtgslpadaapvtalrtvde
paalaghlfeealesngvtvkgdvglggvpadwqdaevladhtsaelseilvpfmkfsnn
ghaemlvksigqetagagtwdaglvgveealsglgvdtaglvlndgsglsrgnlvtadtv
vdllgqagsapwaqtwsaslpvagesdpfvggtlanrmrgtaaegvveaktgtmsgvsal
sgyvpgpegelafsivnnghsgpaplavqdaiavrlaeyaghqape

Timeline for d2wkeb_:

• d2wkeb_ first appeared in SCOPe 2.03
  
• d2wkeb_ appears in SCOPe 2.07