SCOP 1.71: Domain d1igfm1: 1igf M:1-107

Lineage for d1igfm1 (1igf M:1-107)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (126 PDB entries)

8. Domain d1igfm1: 1igf M:1-107 [19814]
   Other proteins in same PDB: d1igfh1, d1igfh2, d1igfj1, d1igfj2, d1igfl2, d1igfm2
   part of Fab B13I2
   complexed with nag

Details for d1igfm1

PDB Entry: 1igf, 2.8 Å

PDB Description: crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 angstroms

SCOP Domain Sequences for d1igfm1:

Sequence; same for both SEQRES and ATOM records:

>d1igfm1 b.1.1.1 (M:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1}
dvlmtqtplslpvslgdqasiscrsnqtillsdgdtylewylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyycfqgshvpptfgggtkleik

Timeline for d1igfm1:

• d1igfm1 first appeared (with stable ids) in SCOP 1.55
  
• d1igfm1 appears in SCOP 1.69
  
• d1igfm1 appears in SCOP 1.73
  
• d1igfm1 appears in the current release, SCOPe 2.08