SCOPe 2.06: Domain d2j21a_: 2j21 A:

Lineage for d2j21a_ (2j21 A:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (8 families)

5. Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)

6. Protein automated matches [190198] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186941] (51 PDB entries)

8. Domain d2j21a_: 2j21 A: [198088]
   automated match to d2j21b_
   complexed with zn; mutant

Details for d2j21a_

PDB Entry: 2j21, 1.6 Å

PDB Description: human p53 core domain mutant m133l-v203a-n239y-n268d-r282w

PDB Compounds: (A:) Cellular tumor antigen p53

SCOPe Domain Sequences for d2j21a_:

Sequence, based on SEQRES records:

>d2j21a_ b.2.5.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svpsqktyqgsygfrlgflhsgtaksvtctyspalnklfcqlaktcpvqlwvdstpppgt
rvramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlraeylddrntfrhs
vvvpyeppevgsdcttihynymcysscmggmnrrpiltiitledssgnllgrdsfevrvc
acpgrdwrteeen

Sequence, based on observed residues (ATOM records):

>d2j21a_ b.2.5.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svpsqktyqgsygfrlgflhsvtctyspalnklfcqlaktcpvqlwvdstpppgtrvram
aiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlraeylddrntfrhsvvvpy
eppevgsdcttihynymcysscmggmnrrpiltiitledssgnllgrdsfevrvcacpgr
dwrteeen

Timeline for d2j21a_:

• d2j21a_ first appeared in SCOPe 2.03
  
• d2j21a_ appears in SCOPe 2.05
  
• d2j21a_ appears in SCOPe 2.07
  
• d2j21a_ appears in the current release, SCOPe 2.08