SCOPe 2.01: Domain d2prgb_: 2prg B:

Lineage for d2prgb_ (2prg B:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (59 PDB entries)
   Uniprot P37231 232-505

8. Domain d2prgb_: 2prg B: [19312]
   Other proteins in same PDB: d2prgc_
   complexed with brl

Details for d2prgb_

PDB Entry: 2prg, 2.3 Å

PDB Description: ligand-binding domain of the human peroxisome proliferator activated receptor gamma

PDB Compounds: (B:) Peroxisome proliferator activated receptor gamma

SCOPe Domain Sequences for d2prgb_:

Sequence, based on SEQRES records:

>d2prgb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d2prgb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtviydmnslmqskevairifqgcqfrsve
avqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvlisegqgfmtre
flkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgllnvkpiediqd
nllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktetdmslhpllqe
iykdly

Timeline for d2prgb_:

• d2prgb_ first appeared (with stable ids) in SCOP 1.55
  
• d2prgb_ appears in SCOP 1.75
  
• d2prgb_ appears in SCOPe 2.02
  
• d2prgb_ appears in the current release, SCOPe 2.08