SCOPe 2.02: Domain d1eree_: 1ere E:

Lineage for d1eree_ (1ere E:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (58 PDB entries)
   Uniprot P03372 307-551

8. Domain d1eree_: 1ere E: [19304]
   complexed with est

Details for d1eree_

PDB Entry: 1ere, 3.1 Å

PDB Description: human estrogen receptor ligand-binding domain in complex with 17beta-estradiol

PDB Compounds: (E:) Estrogen receptor

SCOPe Domain Sequences for d1eree_:

Sequence, based on SEQRES records:

>d1eree_ a.123.1.1 (E:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml
dahr

Sequence, based on observed residues (ATOM records):

>d1eree_ a.123.1.1 (E:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilysefseasmmglltnladrelvhminwakrvpgfvdl
tlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmlla
tssrfrmmnlqgeefvclksiillnsgvytftlksleekdhihrvldkitdtlihlmaka
gltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemldahr

Timeline for d1eree_:

• d1eree_ first appeared (with stable ids) in SCOP 1.55
  
• d1eree_ appears in SCOPe 2.01
  
• d1eree_ appears in SCOPe 2.03
  
• d1eree_ appears in the current release, SCOPe 2.08