SCOPe 2.01: Domain d1pgjb1: 1pgj B:179-478

Lineage for d1pgjb1 (1pgj B:179-478)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
   multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry

4. Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (12 families)
   N-terminal domain is Rossmann-fold with a family-specific C-terminal extension

5. Family a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (2 proteins)
   Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domain

6. Protein 6-phosphogluconate dehydrogenase (6PGD) [48181] (2 species)
   duplication; contains two structural repeats

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [48183] (1 PDB entry)

8. Domain d1pgjb1: 1pgj B:179-478 [18784]
   Other proteins in same PDB: d1pgja2, d1pgjb2
   complexed with so4

Details for d1pgjb1

PDB Entry: 1pgj, 2.82 Å

PDB Description: x-ray structure of 6-phosphogluconate dehydrogenase from the protozoan parasite t. brucei

PDB Compounds: (B:) 6-phosphogluconate dehydrogenase

SCOPe Domain Sequences for d1pgjb1:

Sequence; same for both SEQRES and ATOM records:

>d1pgjb1 a.100.1.1 (B:179-478) 6-phosphogluconate dehydrogenase (6PGD) {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
gagscvkmyhnsgeyailqiwgevfdilramglnndevaavledwksknflksymldisi
aaarakdkdgsyltehvmdrigskgtglwsaqealeigvpapslnmavvsrqftmykter
qanasnapgitqspgytlknkspsgpeikqlydsvciaiiscyaqmfqclremdkvhnfg
lnlpatiatfragcilqgyllkpmteafeknpnisnlmcafqteiraglqnyrdmvalit
sklevsipvlsaslnyvtamftptlkygqlvslqrdvfgrhgyervdkdgresfqwpelq

Timeline for d1pgjb1:

• d1pgjb1 first appeared (with stable ids) in SCOP 1.55
  
• d1pgjb1 appears in SCOP 1.75
  
• d1pgjb1 appears in SCOPe 2.02
  
• d1pgjb1 appears in the current release, SCOPe 2.08