SCOPe 2.04: Domain d3tjda_: 3tjd A:

Lineage for d3tjda_ (3tjd A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (19 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (476 PDB entries)

8. Domain d3tjda_: 3tjd A: [185859]
   automated match to d1u46a_
   complexed with 6tp

Details for d3tjda_

PDB Entry: 3tjd, 2.9 Å

PDB Description: co-crystal structure of Jak2 with thienopyridine 19

PDB Compounds: (A:) Tyrosine-protein kinase JAK2

SCOPe Domain Sequences for d3tjda_:

Sequence, based on SEQRES records:

>d3tjda_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrdfereieil
kslqhdnivkykgvcysagrrnlklimeylpygslrdylqkhkeridhikllqytsqick
gmeylgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespifwya
peslteskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhliell
knngrlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnmag

Sequence, based on observed residues (ATOM records):

>d3tjda_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrdfereieil
kslqhdnivkykgvcysnlklimeylpygslrdylqkhkeridhikllqytsqickgmey
lgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespifwyapesl
teskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhliellknng
rlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdnmag

Timeline for d3tjda_:

• d3tjda_ first appeared in SCOPe 2.01
  
• d3tjda_ appears in SCOPe 2.03
  
• d3tjda_ appears in SCOPe 2.05
  
• d3tjda_ appears in the current release, SCOPe 2.08