SCOPe 2.03: Domain d3nuea_: 3nue A:

Lineage for d3nuea_ (3nue A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.8: Class-II DAHP synthetase [141840] (2 proteins)
   Pfam PF01474

6. Protein Probable DAHP synthetase AroG, phenylalanine-repressible [141841] (1 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [141842] (4 PDB entries)
   Uniprot O53512 1-462

8. Domain d3nuea_: 3nue A: [182556]
   automated match to d2b7oa1
   complexed with ce1, cl, gol, mn, po4, so4, trp

Details for d3nuea_

PDB Entry: 3nue, 2.5 Å

PDB Description: The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from mycobacterium tuberculosis complexed with tryptophan

PDB Compounds: (A:) Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG

SCOPe Domain Sequences for d3nuea_:

Sequence, based on SEQRES records:

>d3nuea_ c.1.10.8 (A:) Probable DAHP synthetase AroG, phenylalanine-repressible {Mycobacterium tuberculosis [TaxId: 1773]}
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgddgepqlfdlsahtvwigertrqidgahiafaqv
ianpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatg
hqviwqcdpmhgnthesstgfktrhfdrivdevqgffevhralgthpggihveitgenvt
eclggaqdisetdlagryetacdprlntqqslelaflvaemlrd

Sequence, based on observed residues (ATOM records):

>d3nuea_ c.1.10.8 (A:) Probable DAHP synthetase AroG, phenylalanine-repressible {Mycobacterium tuberculosis [TaxId: 1773]}
gamnwtvdipidqlpslpplptdlrtrldaalakpaaqqptwpadqalamrtvlesvppv
tvpseivrlqeqlaqvakgeafllqggdcaetfmdntephirgnvrallqmavvltygas
mpvvkvariagqyakprsadidalglrsyrgdmingfapdaaarehdpsrlvrayanasa
amnlvraltssglaslhlvhdwnrefvrtspagaryealateidrglrfmsacgvadrnl
qtaeiyashealvldyeramlrlsdgdgepqlfdlsahtvwigertrqidgahiafaqvi
anpvgvklgpnmtpelaveyverldphnkpgrltlvsrmgnhkvrdllppivekvqatgh
qviwqcdpmhgnthgfktrhfdrivdevqgffevhralgthpggihveitgenvtlggaq
dilagryetacdprlntqqslelaflvaemlrd

Timeline for d3nuea_:

• d3nuea_ first appeared in SCOPe 2.01
  
• d3nuea_ appears in SCOPe 2.02
  
• d3nuea_ appears in SCOPe 2.04
  
• d3nuea_ appears in the current release, SCOPe 2.08, called d3nuea1