SCOPe 2.08: Domain d3l0va_: 3l0v A:

Lineage for d3l0va_ (3l0v A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

5. Family d.92.1.10: TNF-alpha converting enzyme, TACE, catalytic domain [55525] (2 proteins)
   automatically mapped to Pfam PF13574
   automatically mapped to Pfam PF13583

6. Protein TNF-alpha converting enzyme, TACE, catalytic domain [55526] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55527] (20 PDB entries)

8. Domain d3l0va_: 3l0v A: [179846]
   automated match to d1bkce_
   complexed with 724, zn

Details for d3l0va_

PDB Entry: 3l0v, 1.75 Å

PDB Description: crystal structure of catalytic domain of tace with the first hydantoin inhibitor occupying the s1' pocket

PDB Compounds: (A:) Disintegrin and metalloproteinase domain-containing protein 17

SCOPe Domain Sequences for d3l0va_:

Sequence, based on SEQRES records:

>d3l0va_ d.92.1.10 (A:) TNF-alpha converting enzyme, TACE, catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
adpdpmkntckllvvadhrfyrymgrgeestttnylielidrvddiyrntawdnagfkgy
giqieqirilkspqevkpgekhynmaksypneekdawdvkmlleqfsfdiaeeaskvcla
hlftyqdfdmgtlglayggspranshggvcpkayyspvgkkniylnsgltstknygktil
tkeadlvtthelghnfgaehdpdglaecapnedqggkyvmypiavsgdhennkmfsqcsk
qsiyktieskaqecfqers

Sequence, based on observed residues (ATOM records):

>d3l0va_ d.92.1.10 (A:) TNF-alpha converting enzyme, TACE, catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
adpdpmkntckllvvadhrfyrymgrgeestttnylielidrvddiyrntawdnagfkgy
giqieqirilkspqevkpgekhynmaksypneekdawdvkmlleqfsfdiaeeaskvcla
hlftyqdfdmgtlglayggsphggvcpkayyspvgkkniylnsgltstknygktiltkea
dlvtthelghnfgaehdpdglaecapnedqggkyvmypiavsgdhennkmfsqcskqsiy
ktieskaqecfqers

Timeline for d3l0va_:

• d3l0va_ first appeared in SCOPe 2.01
  
• d3l0va_ appears in SCOPe 2.07