Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families) (S)
  5. Family d.92.1.10: TNF-alpha converting enzyme, TACE, catalytic domain [55525] (2 proteins)
    automatically mapped to Pfam PF13574
    automatically mapped to Pfam PF13583
  6. Protein TNF-alpha converting enzyme, TACE, catalytic domain [55526] (1 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [55527] (20 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1bkc:
    1. Domain d1bkca_: 1bkc A: [40331]
      complexed with inn, zn
    2. Domain d1bkcc_: 1bkc C: [40332]
      complexed with inn, zn
    3. Domain d1bkce_: 1bkc E: [40333]
      complexed with inn, zn
    4. Domain d1bkci_: 1bkc I: [40334]
      complexed with inn, zn
  2. Domain(s) for 1zxc:
    1. Domain d1zxca_: 1zxc A: [125769]
      automated match to d1bkce_
      complexed with ih6, zn
    2. Domain d1zxcb_: 1zxc B: [125770]
      automated match to d1bkce_
      complexed with ih6, zn
  3. Domain(s) for 2a8h:
    1. Domain d2a8ha_: 2a8h A: [126402]
      automated match to d1bkce_
      complexed with 4nh, zn
    2. Domain d2a8hb_: 2a8h B: [126403]
      automated match to d1bkce_
      complexed with 4nh, zn
  4. Domain(s) for 2ddf:
    1. Domain d2ddfa_: 2ddf A: [163615]
      automated match to d1bkca_
      complexed with ca, cit, imd, inn, ipa, zn
    2. Domain d2ddfb_: 2ddf B: [163616]
      automated match to d1bkca_
      complexed with ca, cit, imd, inn, ipa, zn
  5. Domain(s) for 2fv5:
    1. Domain d2fv5a1: 2fv5 A:216-475 [164472]
      Other proteins in same PDB: d2fv5a2
      automated match to d1bkce_
      complexed with 541, zn
    2. Domain d2fv5b_: 2fv5 B: [164473]
      Other proteins in same PDB: d2fv5a2
      automated match to d1bkce_
      complexed with 541, zn
  6. Domain(s) for 2fv9:
    1. Domain d2fv9a_: 2fv9 A: [164474]
      automated match to d1bkca_
      complexed with 002, inn, zn
    2. Domain d2fv9b_: 2fv9 B: [164475]
      automated match to d1bkca_
      complexed with 002, inn, zn
  7. Domain(s) for 3b92:
  8. Domain(s) for 3cki:
  9. Domain(s) for 3e8r:
    1. Domain d3e8ra_: 3e8r A: [174757]
      automated match to d1bkce_
      complexed with 615, cit, inn, zn
    2. Domain d3e8rb_: 3e8r B: [174758]
      automated match to d1bkce_
      complexed with 615, cit, inn, zn
  10. Domain(s) for 3edz:
    1. Domain d3edza_: 3edz A: [174868]
      automated match to d1bkce_
      complexed with 550, cit, inn, zn
    2. Domain d3edzb_: 3edz B: [174869]
      automated match to d1bkce_
      complexed with 550, cit, inn, zn
  11. Domain(s) for 3ewj:
    1. Domain d3ewja_: 3ewj A: [175281]
      automated match to d1bkce_
      complexed with 642, inn, zn
    2. Domain d3ewjb_: 3ewj B: [175282]
      automated match to d1bkce_
      complexed with 642, inn, zn
  12. Domain(s) for 3g42:
    1. Domain d3g42a_: 3g42 A: [210347]
      automated match to d3leab_
      complexed with 792, zn
    2. Domain d3g42b_: 3g42 B: [210348]
      automated match to d3leab_
      complexed with 792, zn
    3. Domain d3g42c_: 3g42 C: [210349]
      automated match to d3leab_
      complexed with 792, zn
    4. Domain d3g42d_: 3g42 D: [210350]
      automated match to d3leab_
      complexed with 792, zn
  13. Domain(s) for 3kmc:
    1. Domain d3kmca_: 3kmc A: [179436]
      automated match to d1bkce_
      complexed with 403, inn, zn
    2. Domain d3kmcb_: 3kmc B: [179437]
      automated match to d1bkce_
      complexed with 403, inn, zn
  14. Domain(s) for 3kme:
    1. Domain d3kmea_: 3kme A: [179442]
      automated match to d1bkce_
      complexed with inn, ipa, z59, zn
    2. Domain d3kmeb_: 3kme B: [179443]
      automated match to d1bkce_
      complexed with inn, ipa, z59, zn
  15. Domain(s) for 3l0t:
    1. Domain d3l0ta_: 3l0t A: [179844]
      automated match to d1bkce_
      complexed with inn, ipa, z94, zn
    2. Domain d3l0tb_: 3l0t B: [179845]
      automated match to d1bkce_
      complexed with inn, ipa, z94, zn
  16. Domain(s) for 3l0v:
    1. Domain d3l0va_: 3l0v A: [179846]
      automated match to d1bkce_
      complexed with 724, zn
    2. Domain d3l0vb_: 3l0v B: [179847]
      automated match to d1bkce_
      complexed with 724, zn
  17. Domain(s) for 3le9:
    1. Domain d3le9a_: 3le9 A: [180221]
      automated match to d1bkce_
      complexed with 727, ipa, zn
    2. Domain d3le9b_: 3le9 B: [180222]
      automated match to d1bkce_
      complexed with 727, ipa, zn
  18. Domain(s) for 3lea:
    1. Domain d3leaa_: 3lea A: [180223]
      automated match to d1bkce_
      complexed with ipa, z93, zn
    2. Domain d3leab_: 3lea B: [180224]
      automated match to d1bkce_
      complexed with ipa, z93, zn
  19. Domain(s) for 3lgp:
    1. Domain d3lgpa_: 3lgp A: [180282]
      automated match to d1bkce_
      complexed with 50x, zn
    2. Domain d3lgpb_: 3lgp B: [180283]
      automated match to d1bkce_
      complexed with 50x, zn
  20. Domain(s) for 3o64:
    1. Domain d3o64a_: 3o64 A: [182823]
      automated match to d1bkce_
      complexed with 786, ca, inn, ipa, zn
    2. Domain d3o64b_: 3o64 B: [182824]
      automated match to d1bkce_
      complexed with 786, ca, inn, ipa, zn

More info for Species Human (Homo sapiens) [TaxId:9606] from d.92.1.10 TNF-alpha converting enzyme, TACE, catalytic domain

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.92.1.10 TNF-alpha converting enzyme, TACE, catalytic domain: